SimInhale - Simulation and pharmaceutical technologies for advanced patient-tailored inhaled medicines

Abstract:

As a result of the culmination of several scientific and technological developments, we are on the verge of technological breakthroughs in the field of inhaled medicines that will revolutionize the treatment of many acute or chronic respiratory and systemic illnesses. However, knowledge in the field is vertically fragmented and compartmentalized in disciplines. As a result, current developments are not necessarily synergistic and supportive of each other. The prospect of patient-tailored inhaled medicines necessitates a much closer coordination of research and development activities. Simlnhale aims to create a pan-European network of experts in order to: i) advance particle designs for improved deposition and interaction with lung tissue, ii) promote realistic computer simulations of particle aerosolization, delivery and deposition, iii) promote patient-tailored inhaled medicines, iv) promote integration of device and formulation design, and v) promote critical assessment of toxicity issues and related risks. Making a new generation of advanced inhaled pharmaceuticals available to patients in a shorter period of time will have enormous social benefits.

Project details

Action member: Gaia Colombo

Funding source: COST

Start date 04/05/2015 - end date 03/11/2019

website

Participants

  • University of Cyprus, Cyprus - Chair
  • Research Center Pharmaceutical Engineering GmbH (RCPE), Austria
  • Medical University of Graz, Austria
  • FLUIDDA, Belgium
  • Ghent University, Belgium
  • University of Cyprus, Cyprus
  • Institute of Chemical Process Fundamentals of the CAS, v.v.i., Czech Republic
  • Brno University of Technology, Czech Republic
  • University of Copenhagen, Denmark
  • Université Paris Sud, France
  • Inserm, France
  • Martin-Luther-Universität Halle-Wittenberg, Germany
  • Otto-von-Guericke University, Germany
  • Technical University of Crete, Greece
  • Centre for Energy Research, Hungarian Academy of Sciences, Hungary
  • Trinity College Dublin, Ireland
  • Bar-Ilan University, Israel
  • Technion - Israel Institute of Technology, Israel
  • University of Parma, Italy
  • University of Ferrara, Italy
  • University of Malta, Malta
  • University of Montenegro Faculty of Pharmacy, Montenegro
  • Medspray BV, Netherlands
  • Simula Research Laboratory, Norway
  • INFARMED IP, Portugal
  • Universidade de Lisboa, Portugal
  • "Petru Poni" Institute of Macromolecular Chemistry, Romania
  • Medicine qnd Phqrmacy Grigore T Popa Iasi, Romania
  • University of Kragujevac, Serbia
  • University of Belgrade, Serbia
  • University of Ljubljana, Slovenia
  • Barcelona Supercomputing Center, Spain
  • ETSEIAT-CTTC, Spain
  • MVIC Medicon Village, Sweden
  • Luleå University of Technology, Sweden
  • IDSIA - Institute Dalle Molle for Artificial Intelligence, Switzerland
  • University of Geneva, Switzerland
  • Istanbul University, Turkey
  • University of Birmingham, United Kingdom
  • University of Southampton, United Kingdom
  • BioNanoNet Forschungsgesellschaft mbH, Austria
  • CNRS, France
  • University of Montenegro, Montenegro
  • University of Groningen - Pharmaceutical Technology and Biopharmacy Dept, Netherlands
  • Instituto Superior Técnico, Portugal
  • Universitat Politècnica de Catalunya (UPC), Spain
  • King's College London, United Kingdom
  • Queen's University Belfast, United Kingdom
  • National University of Singapore, Singapore
  • Simulations Plus, Inc., United States
  • Royal Melbourne Institute of Technology, Australia