BIOMATERIALS AND THEIR TRANSMISSION
Academic year and teacher
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- Versione italiana
- Academic year
- 2022/2023
- Teacher
- ELISABETTA ESPOSITO
- Credits
- 12
- Didactic period
- Primo Semestre
Training objectives
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Modulo: 019356/3 - TECNOLOGIA FARMACEUTICA
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Biomaterials and biocompatible synthetic materials:
Students will be able to know the various types of materials of biomedical interest, to distinguish them on the basis of the main properties and application purposes.
Pharmaceutical Technology:
The student will be able to apply the scientific principles relative to the design, production and quality control of conventional and nanotechnological pharmaceutical formulations. In addition the student will be able to evaluate the drawbacks associated to production and use of the studied pharmaceutical forms.
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Modulo: 69520 - BIOMATERIALE E MATERIALI SINTETICI BIOCOMPATIBILI
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Biomaterials and biocompatible synthetic materials:
Students will be able to know the various types of materials of biomedical interest, to distinguish them on the basis of the main chemical and structural features as well as properties and application purposes.
Pharmaceutical Technology:
The student will be able to apply the scientific principles relative to the design, production and quality control of conventional and nanotechnological pharmaceutical formulations. In addition the student will be able to evaluate the drawbacks associated to production and use of the studied pharmaceutical forms. Prerequisites
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Modulo: 019356/3 - TECNOLOGIA FARMACEUTICA
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Biomaterials and biocompatible synthetic materials:
Knowledge of organic chemistry, analytical chemistry and physics
Pharmaceutical Technology:
The student must have organic chemistry, physics and mathematical knowledge.
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Modulo: 69520 - BIOMATERIALE E MATERIALI SINTETICI BIOCOMPATIBILI
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Biomaterials and biocompatible synthetic materials:
Knowledge of physic, general and organic chemistry,
Pharmaceutical Technology:
The student must have organic chemistry, physics and mathematical knowledge. Course programme
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Modulo: 019356/3 - TECNOLOGIA FARMACEUTICA
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Biomaterials and biocompatible synthetic materials:
Definition and classification of biomaterials: metals and their alloys, ceramics, thermoplastic and thermosetting polymers, composites, biodegradable and bioactive materials.
Introduction to the structure of solids.
Properties of materials of biomedical interest: mechanical, thermal and surface properties.
Definition of polymer, average molecular weight, polydispersity, copolymers. Peculiarities of solid state polymers. Polymers of biomedical interest: polyurethanes, silicones, fluoropolymers, polyacrylates, biodegradable and bioabsorbable polymers. Natural polymers: proteins and polysaccharides. Semi-synthetic polymers.
The hydrogels. The composites.
Methods of transformation of thermoplastic and thermosetting materials. Preparation of membranes, sponges. Surface modification methods. 3D printing.
Main methods of characterization of materials of biomedical interest.
Pharmaceutical Technology:
-Definition of medicinal product and pharmaceutical form
- Solutions and their properties, the dissolution process
- Powders
- Surface and interface phenomena
- Classification and properties of surfactants
- Disperse systems and colloidal dispersions
- Micellar systems and pharmaceutical applications
- Suspensions: chemical-physical characteristics, preparation, stability
- Emulsions: chemical-physical characteristics, preparation, stability
- Parenteral preparations
- Notes on sterilization processes
- Notes on freeze-drying processes
- Pharmaceutical and nanomedicine nanotechnologies
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Modulo: 69520 - BIOMATERIALE E MATERIALI SINTETICI BIOCOMPATIBILI
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Biomaterials and biocompatible synthetic materials:
Definition and classification of biomaterials: metals and their alloys, ceramics, thermoplastic and thermosetting polymers, composites, biodegradable and bioactive materials.
Introduction to the structure of solids.
Properties of materials of biomedical interest: mechanical, thermal and surface properties.
Definition of polymer, average molecular weight, polydispersity, copolymers. Peculiarities of solid state polymers. Polymers of biomedical interest: polyurethanes, silicones, fluoropolymers, polyacrylates, biodegradable and bioabsorbable polymers. Natural polymers: proteins and polysaccharides. Semi-synthetic polymers.
The hydrogels. The composites.
Methods of transformation of thermoplastic and thermosetting materials. Preparation of membranes, sponges. Surface modification methods. 3D printing.
Main methods of characterization of materials of biomedical interest.
Pharmaceutical Technology:
-Definition of medicinal product and pharmaceutical form
- Solutions and their properties, the dissolution process
- Powders
- Surface and interface phenomena
- Classification and properties of surfactants
- Disperse systems and colloidal dispersions
- Micellar systems and pharmaceutical applications
- Suspensions: chemical-physical characteristics, preparation, stability
- Emulsions: chemical-physical characteristics, preparation, stability
- Parenteral preparations
- Notes on sterilization processes
- Notes on freeze-drying processes
- Pharmaceutical and nanomedicine nanotechnologies Didactic methods
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Modulo: 019356/3 - TECNOLOGIA FARMACEUTICA
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The course will be delivered through theoretical lessons aimed at exposing and explaining the contents of the program with the help of videos showing some production processes
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Modulo: 69520 - BIOMATERIALE E MATERIALI SINTETICI BIOCOMPATIBILI
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The course will be delivered through theoretical lessons aimed at exposing and explaining the contents of the program with the help of videos showing some production processes Learning assessment procedures
- The actual acquisition of knowledge and skills provided by the course will be ascertained by a written evaluation. The objective of the examination is to verify the level of achievement of the previously indicated educational objectives. By the test the ability to connect and compare different aspects treated during the course will be evaluated.
The test consists of 16 multiple choice questions (a-d). A score of 1 point each. No penalties are given to unanswered questions or wrong answers. Reference texts
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Modulo: 019356/3 - TECNOLOGIA FARMACEUTICA
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Specific topics can be explored in the following texts:
Biomaterials and biocompatible synthetic materials:
Biomedical Materials
Roger Narayan
Springer Nature Switzerland AG 2021
Fundamentals of Polymer Science: An Introductory Text, Second Edition
Michael M. Coleman, Paul C. Painter
CRC Press; 30 aprile 1998
Pharmaceutical Technology:
Michael E. Aulton and Kevin M.G. Taylor
Aulton's Pharmaceutics The Design and Manufacture of Medicines.
Editore: Churchill Livingstone - Elsevier. 4th Edition.
ISBN 978-0-7020-4290-4
Loyd V. Allen.
Remington: The Science and Practice of Pharmacy.
Editore: Pharmaceutical Press; 22nd Revised edition
A.T. Florence, David Attwood.
Physicochemical Principles of Pharmacy.
Editore: Pharmaceutical Pr; 5th edizione
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Modulo: 69520 - BIOMATERIALE E MATERIALI SINTETICI BIOCOMPATIBILI
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Slides provided by the teacher. Specific topics can be explored in the following texts:
Biomaterials and biocompatible synthetic materials:
Biomedical Materials
Roger Narayan
Springer Nature Switzerland AG 2021
Fundamentals of Polymer Science: An Introductory Text, Second Edition
Michael M. Coleman, Paul C. Painter
CRC Press; 30 aprile 1998
Pharmaceutical Technology:
Michael E. Aulton and Kevin M.G. Taylor
Aulton's Pharmaceutics The Design and Manufacture of Medicines.
Editore: Churchill Livingstone - Elsevier. 4th Edition.
ISBN 978-0-7020-4290-4
Loyd V. Allen.
Remington: The Science and Practice of Pharmacy.
Editore: Pharmaceutical Press; 22nd Revised edition
A.T. Florence, David Attwood.
Physicochemical Principles of Pharmacy.
Editore: Pharmaceutical Pr; 5th edizione
