Salta ai contenuti. | Salta alla navigazione

Strumenti personali

ETIOPATHOGENESIS OF DISEASES

Academic year and teacher
If you can't find the course description that you're looking for in the above list, please see the following instructions >>
Versione italiana
Academic year
2022/2023
Teacher
ELISABETTA CASELLI
Credits
8
Didactic period
Secondo Semestre

Training objectives

------------------------------------------------------------
Modulo: 007086 - FISIOLOGIA
------------------------------------------------------------
HUMAN PHYSIOLOGY
To give a complete and integrate vision of the human apparatus functions and the principles of clinical biochemistry.

------------------------------------------------------------
Modulo: 45826 - PATOLOGIA GENERALE
------------------------------------------------------------
GENERAL PATHOLOGY
Learning of basic Pathology: etiology, adaptations, cell damage and death, inflammatory reactions, healing, alterations of cell proliferation and differentiation, tumors. Knowledge of main immune-pathologic dieases: hypersensitivity reactions and autoimmune diseases.

------------------------------------------------------------
Modulo: 53051 - MICROBIOLOGIA ORALE
------------------------------------------------------------
ORAL MICROBIOLOGY
Knowledge of the infectious agents residing temporarily or permanently in the oral cavity, and causing diseases of the oral cavity itself or systemic diseases. Epidemiology, the way of transmission, the defense mechanisms of the host, and the pathogenic mechanisms of the human pathogens specified in the course program. Knowledge of the the mechanisms leading to the acquisition and evolution of the oral microbiota, and its impact on the onset of the main diseases of the oral cavity with microbiological etiology (dental caries and periodontal diseases).

------------------------------------------------------------
Modulo: 53065 - MICROBIOLOGIA GENERALE (mutua dall'attività formativa MICROBIOLOGIA - 28137 del CdS ODONTOIATRIA E PROTESI DENTARIA - 1024)
------------------------------------------------------------
MICROBIOLOGY
The student, at the end of the Microbiology course, must have acquired knowledge regarding the composition, structure and biological cycle of Bacteria, Viruses and Mycetes. The student will know the bases of the diagnostic procedures used in Microbiology and the mechanisms by which the microorganisms can cause the diseases. Furthermore, the student will understand the interactions between microorganisms and host, with particular attention to the bases of the bacterial, viral and mycetes pathogenesis, and to the immune response of the host. In addition, the student will know the principles of bacterial genetics related to the bacterial pathogenicity and acquisition of resistance to antibacterial drugs, the host defense mechanisms, and the damage mechanisms of the main human pathogens. The student will know the mechanism of action of the main antibacterial drugs and the molecular mechanisms responsible for the drug resistance. The student also will know the structural and biological characteristics of the human pathogen listed in the course program.

Prerequisites

------------------------------------------------------------
Modulo: 007086 - FISIOLOGIA (mutua dall'attività formativa FISIOLOGIA UMANA - 23783 del CdS INFERMIERISTICA (abilitante alla professione sanitaria di Infermiere) - 1055)
------------------------------------------------------------
Basic knowledge of chemistry, histology and genetics. Knowledge of biochemistry and molecular biology, with respect to: structure and function of cellular components, structure and synthesis of proteins and nucleic acids. Knowledge of human anatomy. Elements of microscopic anatomy and physics.

------------------------------------------------------------
Modulo: 45826 - PATOLOGIA GENERALE (mutua dall'attività formativa PATOLOGIA GENERALE - 45826 del CdS DIETISTICA (abilitante alla professione sanitaria di Dietista) - 1050)
------------------------------------------------------------
Basic knowledge of chemistry, histology and genetics. Knowledge of biochemistry and molecular biology, with respect to: structure and function of cellular components, structure and synthesis of proteins and nucleic acids. Knowledge of human anatomy. Elements of microscopic anatomy and physics.

------------------------------------------------------------
Modulo: 53051 - MICROBIOLOGIA ORALE
------------------------------------------------------------
Basic knowledge of chemistry, histology and genetics. Knowledge of biochemistry and molecular biology, with respect to: structure and function of cellular components, structure and synthesis of proteins and nucleic acids. Knowledge of human anatomy. Elements of microscopic anatomy and physics.

------------------------------------------------------------
Modulo: 53065 - MICROBIOLOGIA GENERALE (mutua dall'attività formativa MICROBIOLOGIA - 28137 del CdS ODONTOIATRIA E PROTESI DENTARIA - 1024)
------------------------------------------------------------
Basic knowledge of chemistry, histology and genetics. Knowledge of biochemistry and molecular biology, with respect to: structure and function of cellular components, structure and synthesis of proteins and nucleic acids. Knowledge of human anatomy. Elements of microscopic anatomy and physics.

Course programme

------------------------------------------------------------
Modulo: 007086 - FISIOLOGIA (mutua dall'attività formativa FISIOLOGIA UMANA - 23783 del CdS INFERMIERISTICA (abilitante alla professione sanitaria di Infermiere) - 1055)
------------------------------------------------------------
PHYSIOLOGY
Physiology of nerve and muscle: resting potential, the action potential and its conduction, synaptic transmission, neuromuscular transmission. Mechanism of muscle contraction.
Physiology of heart and circulation: vascular system and principles of hemodynamics; the heart as a pump; the electrical activity of the heart and its control; normal circulatory function and its regulation. Capillary circulation and exchange of materials.
Endocrine glands: pituitry gland, thyroid gland, parathyroid glands, adrenal cortex, endocrine functions of the pancreas, menstrual cycle.
Respiration: mechanical aspects of respiration, transport of oxigen and carbon dioxide by the blood. nervous and chemical control of respiration at rest.
Physiology of the kidney: body water and fluid compartments. Structure of the kidney, formation of plasma ultrafiltrate in the glomerulus, tubular function, renal control of body water and salt, renal regulation of acid-base balance, renal clearance.

------------------------------------------------------------
Modulo: 45826 - PATOLOGIA GENERALE (mutua dall'attività formativa PATOLOGIA GENERALE - 45826 del CdS DIETISTICA (abilitante alla professione sanitaria di Dietista) - 1050)
------------------------------------------------------------
GENERAL PATHOLOGY
Cell adaptations: hypertrophy, hyperplasia, atrophy, metaplasia, dysplasia.
Cell death: necrosis and apoptosis.
Intracellular accumulations. Accumulation in the connective tissues: amyloidosis
Immune System: components and general functions.
Acute inflammation: vascular phenomena, leukocyte exudation, chemical mediators. Features of exudates. Types of acute inflammatory reactions.
Chronic inflammation: interstitial and granulomatous. Generalities and examples. Tuberculosis
The repair process: phases and mediators. Systemic effects of inflammation: fever, leukocytosis, acute phase proteins
Tumors: characteristics of benign and malignant tumors. Histogenetic classification, grading, staging. Molecular basis of the neoplastic process. Stages of carcinogenesis. Tumor growth, tumor progression and metastasis. Immune response against tumors. Local and systemic effects of the tumor. Hypersensitivity reactions.
Autoimmunity: general characteristics and examples. Diabetes mellitus type I. Rheumatoid Arthritis. Multiple sclerosis. Myasthenia gravis. Celiac disease. LES.
Regulation of body weight. Obesity and associated diseases
Diabetes mellitus type 2.

------------------------------------------------------------
Modulo: 53051 - MICROBIOLOGIA ORALE
------------------------------------------------------------
ORAL MICROBIOLOGY
Microbiota of the oral cavity. Oral Bacteria, Mycetes and viruses, and associated diseases.
Oral microbial ecosystem; microbiology of the dental plaque; microbiology of the tooth decay; microbiology of the periodontum and of the periodontal diseases.

------------------------------------------------------------
Modulo: 53065 - MICROBIOLOGIA GENERALE (mutua dall'attività formativa MICROBIOLOGIA - 28137 del CdS ODONTOIATRIA E PROTESI DENTARIA - 1024)
------------------------------------------------------------
GENERAL MICROBIOLOGY
Principles of sterilization and disinfection. Principles of Immunology. Vaccines.
Normal human microbiota. Infections and their routes of transmission.
Bacteriology: bacterial taxonomy; composition and structure of the bacterial cell; bacterial metabolism; bacterial reproduction; spore production; genetic recombination processes; pathogenic action of bacteria, virulence and toxigenicity; bacterial toxins; antibiotics and drug-resistance.
Staphylococcus. Streptococcus. Neisseria. Corynebacterium. Enterobacteriaceae. Spore-producing bacilli. Mycobacteria.
Virology: classification, composition and structure of viruses; viral replication; virus culture and titration; pathogenic action of viruses and pathogenesis of viral diseases; antiviral defenses; interferons and antiviral drugs.
Herpesvirus. Papillomavirus. Orthomyxovirus. Paramyxovirus. Picornavirus. Retrovirus. Hepatitis viruses.
Mycetes: human pathogenic Mycetes; mechanism of pathogenesis and anti-mycosis drugs; opportunistic Mycetes (Candida).

Didactic methods

------------------------------------------------------------
Modulo: 007086 - FISIOLOGIA (mutua dall'attività formativa FISIOLOGIA UMANA - 23783 del CdS INFERMIERISTICA (abilitante alla professione sanitaria di Infermiere) - 1055)
------------------------------------------------------------
Lecture, laboratory exercise

------------------------------------------------------------
Modulo: 45826 - PATOLOGIA GENERALE (mutua dall'attività formativa PATOLOGIA GENERALE - 45826 del CdS DIETISTICA (abilitante alla professione sanitaria di Dietista) - 1050)
------------------------------------------------------------
Lecture, laboratory exercise

------------------------------------------------------------
Modulo: 53051 - MICROBIOLOGIA ORALE
------------------------------------------------------------
Lectures

------------------------------------------------------------
Modulo: 53065 - MICROBIOLOGIA GENERALE (mutua dall'attività formativa MICROBIOLOGIA - 28137 del CdS ODONTOIATRIA E PROTESI DENTARIA - 1024)
------------------------------------------------------------
Lecture, laboratory exercise

Learning assessment procedures

THE FINAL GRADE IS A WEIGHTED AVERAGE OF THE MARKS OBTAINED IN EACH TESTS.
PHYSIOLOGY
The oral exam, lasting about twenty minutes, provides a teacher's question to test the basic knowledge of the main physiological mechanisms of the body. Language property, exhibit clarity, reasoning skills, are also evaluated.
GENERAL PATHOLOGY
Multiple choice test. 31 questions in 30 minutes. 1 point for every correct answer, 0 point for every incorrect or invalid answer. 18 points are necessary to pass the exam. Maximum score: 30+L.
GENERAL MICROBIOLOGY
The exam will consist of a written test, including 31 multiple-choice questions in 30 minutes. The score of the written test will be evaluated as follows: each correct multiple-choice answer = 1; each correct open answer = 2; each incorrect multiple-choice or open answer = 0 (total final score for a totally correct test = 31, i.e. 30L).
ORAL MICROBIOLOGY
The exam will consist of a written test, including 31 multiple-choice questions in 30 minutes. The score of the written test will be evaluated as follows: each correct multiple-choice answer = 1; each correct open answer = 2; each incorrect multiple-choice or open answer = 0 (total final score for a totally correct test = 31, i.e. 30L).

Reference texts

------------------------------------------------------------
Modulo: 007086 - FISIOLOGIA (mutua dall'attività formativa FISIOLOGIA UMANA - 23783 del CdS INFERMIERISTICA (abilitante alla professione sanitaria di Infermiere) - 1055)
------------------------------------------------------------
PHYSIOLOGY
C.L. Stanfield, Fisiologia, EdiSES, 2004

------------------------------------------------------------
Modulo: 45826 - PATOLOGIA GENERALE (mutua dall'attività formativa PATOLOGIA GENERALE - 45826 del CdS DIETISTICA (abilitante alla professione sanitaria di Dietista) - 1050)
------------------------------------------------------------
GENERAL PATHOLOGY
Teacher’s handouts.
Pontieri G.M. (2012), Patologia e Fisiopatologia generale per Corsi di Laurea in Professioni Sanitarie, Piccin Editore, Padova

------------------------------------------------------------
Modulo: 53051 - MICROBIOLOGIA ORALE
------------------------------------------------------------
GENERAL MICROBIOLOGY
Harvey, Champe, Fisher, Le basi della microbiologia, Zanichelli
ORAL MICROBIOLOGY
Lamont, Burne, Lantz, LeBlanc, Microbiologia ed immunologia del cavo orale, EMSI Ed.

------------------------------------------------------------
Modulo: 53065 - MICROBIOLOGIA GENERALE (mutua dall'attività formativa MICROBIOLOGIA - 28137 del CdS ODONTOIATRIA E PROTESI DENTARIA - 1024)
------------------------------------------------------------
GENERAL MICROBIOLOGY
Harvey, Champe, Fisher, Le basi della microbiologia, Zanichelli