MOLECULAR AND FUNCTIONAL BASES OF LIFE
Academic year and teacher
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- Versione italiana
- Academic year
- 2022/2023
- Teacher
- TIZIANA BELLINI
- Credits
- 8
- Didactic period
- Primo Semestre
Training objectives
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Modulo: 000061/1 - BIOCHIMICA
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Acquired knowledge: basic knowledge of structure and function and transformation of macromolecules by the human body; basic knowledge to understand physiological and pathological processes in healthy or disease conditions.
Skills: use of the acquired chemical-biochemical knowledge to tackle the study of other biomedical disciplines.
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Modulo: 009824/2 - CHIMICA MEDICA
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MEDICAL CHEMISTRY AND BIOCHEMISTRY
Acquired knowledge: basic knowledge of structure and function and transformation of macromolecules by the human body; basic knowledge to understand physiological and pathological processes in healthy or disease conditions.
Skills: use of the acquired chemical-biochemical knowledge to tackle the study of other biomedical disciplines. Use of simple calculation to perform dilution of drugs.
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Modulo: 010216/1 - STATISTICA MEDICA
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The course is intended to teach basic concepts of descriptive and inferential statistics applied to the biomedical field.
The teaching program is designed to providing the basic knowledge for interpreting the main statistical results reported in scientific evidence.
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Modulo: 015421/1 - GENETICA MEDICA
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MEDICAL CHEMISTRY AND BIOCHEMISTRY
Acquired knowledge: basic knowledge of structure and function and transformation of macromolecules by the human body; basic knowledge to understand physiological and pathological processes in healthy or disease conditions.
Skills: use of the acquired chemical-biochemical knowledge to tackle the study of other biomedical disciplines. Use of simple calculation to perform dilution of drugs.
APPLIED BIOLOGY
Knowledge of the organization of the living organisms at the cellular level. Knowledge on the macromolecules of the living organisms, their properties, the modes of replication and reproduction. How the genetic information are passed from DNA to RNA and from RNA to proteins
MEDICAL GENETICS
To provide the fundamental knowledge on the genetic basis of the transmission of hereditary characters.
To analyze the molecular mechanisms causing hereditary genetic diseases in individuals and families.
Understanding the inheritance mechanism of inherited genetic diseases by pedigree analysis.
APPLIED PHYSICS
Learning of physical quantities and applications useful to characteristic disciplines of the course.
MEDICAL STATISTICS
The course is intended to teach basic concepts of descriptive and inferential statistics applied to the biomedical field.
The teaching program is designed to providing the basic knowledge for interpreting the main statistical results reported in scientific evidence.
COMPUTER SCIENCES
Introduction of some basic concepts of computer science. Using the PC under Microsoft Windows, Office Automation, the Web browsing and e-mail. The course is conducted in accordance with the standard ECDL
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Modulo: 015440/3 - BIOLOGIA APPLICATA
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MEDICAL CHEMISTRY AND BIOCHEMISTRY
Acquired knowledge: basic knowledge of structure and function and transformation of macromolecules by the human body; basic knowledge to understand physiological and pathological processes in healthy or disease conditions.
Skills: use of the acquired chemical-biochemical knowledge to tackle the study of other biomedical disciplines. Use of simple calculation to perform dilution of drugs.
APPLIED BIOLOGY
Knowledge of the organization of the living organisms at the cellular level. Knowledge on the macromolecules of the living organisms, their properties, the modes of replication and reproduction. How the genetic information are passed from DNA to RNA and from RNA to proteins
MEDICAL GENETICS
To provide the fundamental knowledge on the genetic basis of the transmission of hereditary characters.
To analyze the molecular mechanisms causing hereditary genetic diseases in individuals and families.
Understanding the inheritance mechanism of inherited genetic diseases by pedigree analysis.
APPLIED PHYSICS
Learning of physical quantities and applications useful to characteristic disciplines of the course.
MEDICAL STATISTICS
The course is intended to teach basic concepts of descriptive and inferential statistics applied to the biomedical field.
The teaching program is designed to providing the basic knowledge for interpreting the main statistical results reported in scientific evidence.
COMPUTER SCIENCES
Introduction of some basic concepts of computer science. Using the PC under Microsoft Windows, Office Automation, the Web browsing and e-mail. The course is conducted in accordance with the standard ECDL
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Modulo: 26804 - FISICA APPLICATA
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MEDICAL CHEMISTRY AND BIOCHEMISTRY
Acquired knowledge: basic knowledge of structure and function and transformation of macromolecules by the human body; basic knowledge to understand physiological and pathological processes in healthy or disease conditions.
Skills: use of the acquired chemical-biochemical knowledge to tackle the study of other biomedical disciplines. Use of simple calculation to perform dilution of drugs.
APPLIED BIOLOGY
Knowledge of the organization of the living organisms at the cellular level. Knowledge on the macromolecules of the living organisms, their properties, the modes of replication and reproduction. How the genetic information are passed from DNA to RNA and from RNA to proteins
MEDICAL GENETICS
To provide the fundamental knowledge on the genetic basis of the transmission of hereditary characters.
To analyze the molecular mechanisms causing hereditary genetic diseases in individuals and families.
Understanding the inheritance mechanism of inherited genetic diseases by pedigree analysis.
APPLIED PHYSICS
Learning of physical quantities and applications useful to characteristic disciplines of the course.
MEDICAL STATISTICS
The course is intended to teach basic concepts of descriptive and inferential statistics applied to the biomedical field.
The teaching program is designed to providing the basic knowledge for interpreting the main statistical results reported in scientific evidence.
COMPUTER SCIENCES
Introduction of some basic concepts of computer science. Using the PC under Microsoft Windows, Office Automation, the Web browsing and e-mail. The course is conducted in accordance with the standard ECDL
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Modulo: 26805 - INFORMATICA
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MEDICAL CHEMISTRY AND BIOCHEMISTRY
Acquired knowledge: basic knowledge of structure and function and transformation of macromolecules by the human body; basic knowledge to understand physiological and pathological processes in healthy or disease conditions.
Skills: use of the acquired chemical-biochemical knowledge to tackle the study of other biomedical disciplines. Use of simple calculation to perform dilution of drugs.
APPLIED BIOLOGY
Knowledge of the organization of the living organisms at the cellular level. Knowledge on the macromolecules of the living organisms, their properties, the modes of replication and reproduction. How the genetic information are passed from DNA to RNA and from RNA to proteins
MEDICAL GENETICS
To provide the fundamental knowledge on the genetic basis of the transmission of hereditary characters.
To analyze the molecular mechanisms causing hereditary genetic diseases in individuals and families.
Understanding the inheritance mechanism of inherited genetic diseases by pedigree analysis.
APPLIED PHYSICS
Learning of physical quantities and applications useful to characteristic disciplines of the course.
MEDICAL STATISTICS
The course is intended to teach basic concepts of descriptive and inferential statistics applied to the biomedical field.
The teaching program is designed to providing the basic knowledge for interpreting the main statistical results reported in scientific evidence.
COMPUTER SCIENCES
Introduction of some basic concepts of computer science. Using the PC under Microsoft Windows, Office Automation, the Web browsing and e-mail. The course is conducted in accordance with the standard ECDL
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Modulo: 53261 - SEMINARIO DI INFORMATICA
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MEDICAL CHEMISTRY AND BIOCHEMISTRY
Acquired knowledge: basic knowledge of structure and function and transformation of macromolecules by the human body; basic knowledge to understand physiological and pathological processes in healthy or disease conditions.
Skills: use of the acquired chemical-biochemical knowledge to tackle the study of other biomedical disciplines. Use of simple calculation to perform dilution of drugs.
APPLIED BIOLOGY
Knowledge of the organization of the living organisms at the cellular level. Knowledge on the macromolecules of the living organisms, their properties, the modes of replication and reproduction. How the genetic information are passed from DNA to RNA and from RNA to proteins
MEDICAL GENETICS
To provide the fundamental knowledge on the genetic basis of the transmission of hereditary characters.
To analyze the molecular mechanisms causing hereditary genetic diseases in individuals and families.
Understanding the inheritance mechanism of inherited genetic diseases by pedigree analysis.
APPLIED PHYSICS
Learning of physical quantities and applications useful to characteristic disciplines of the course.
MEDICAL STATISTICS
The course is intended to teach basic concepts of descriptive and inferential statistics applied to the biomedical field.
The teaching program is designed to providing the basic knowledge for interpreting the main statistical results reported in scientific evidence.
COMPUTER SCIENCES
Introduction of some basic concepts of computer science. Using the PC under Microsoft Windows, Office Automation, the Web browsing and e-mail. The course is conducted in accordance with the standard ECDL Prerequisites
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Modulo: 000061/1 - BIOCHIMICA
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Basic concepts of chemistry. Very basic knowledge of the structure of atoms, nature of chemical bonds and aggregation states of the matter.
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Modulo: 009824/2 - CHIMICA MEDICA
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Basic concepts of chemistry and math. Very basic knowledge of the structure of atoms, nature of chemical bonds, stoichiometry and aggregation states of the matter.
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Modulo: 010216/1 - STATISTICA MEDICA
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Conoscenza di base della epidemiologia e della biostatistica.
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Modulo: 015421/1 - GENETICA MEDICA
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Basic concepts of chemistry and math.
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Modulo: 015440/3 - BIOLOGIA APPLICATA
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Basic concepts of general and organic chemistry.
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Modulo: 26804 - FISICA APPLICATA
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Basic concepts of chemistry and math. Very basic knowledge of the structure of atoms, nature of chemical bonds, stoichiometry and aggregation states of the matter.
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Modulo: 26805 - INFORMATICA
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COMPUTER SCIENCES
Basic understanding of the terminology commonly used in computer
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Modulo: 53261 - SEMINARIO DI INFORMATICA
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COMPUTER SCIENCES
Basic understanding of the terminology commonly used in computer Course programme
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Modulo: 000061/1 - BIOCHIMICA
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Structure and function of carbohydrates, lipids, amino acids and proteins. Hemoglobin and myoglobin. Enzymes. ATP and Metabolism with the different steps in energy extraction from nutrients. Localization of metabolic pathways in the cell. Coenzymes and main metabolic pathways.
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Modulo: 009824/2 - CHIMICA MEDICA
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MEDICAL CHEMISTRY
Atom constituents and radioactivity. Chemical bonds. Gas Laws. Solutions. Solubility of gases in liquids. Chemical equilibrium: Le Chatelier’s principle and Mass Action Law. Acids, bases and salts. blood Buffer solutions, pH, , Osmotic pressure and osmolarity: hyper-hypo,isotonic and saline solutions. Basic information on organic chemistry (only functional groups recognition).
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Modulo: 010216/1 - STATISTICA MEDICA
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The course will be structured around the following topics:
1) Descriptive Statistics: central tendency and variability indexes.
2) The fundamentals of probability as applied to diagnostic tests and biomedical research.
4) Statistical inference: Interval estimates (confidence intervals) and hypothesis testing with applications and examples in clinical research.
6) Inference on categorical data: the main measures of association such as Odds Ratio (OR) and Relative Risk (RR).
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Modulo: 015421/1 - GENETICA MEDICA
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MEDICAL GENETICS
General concepts of genetics: genes, alleles, genotype, phenotype. Mendel's laws. Independent genes and associated genes. Codominance and multiple allelia (examples: System AB0 and HLA). Genomic, chromosomal and gene mutations with examples of associated pathologies. Mendelian transmission of autosomal dominant, autosomal recessive and X-associated genetic diseases and transmission of mitochondrial diseases. Analysis of family trees.
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Modulo: 015440/3 - BIOLOGIA APPLICATA
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Chemical composition of the living organisms. General characteristics of the biological macromolecules. DNA structure, composition, mechanism of replication and the main enzymes involved. Genomic organization of the prokaryotic and eukaryotic cells. Chromatin and nucleic acids as vectors of the genetic information. Eukaryotic cell: structure, function, multiplication. Compartments of the eukaryotic cell. Cytoplasmic organelles. Cell membrane. Nucleous, Nucleolus. Transcription, Translation. The cell cycle. Mitosis, Meiosis. The Bacterial cell.
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Modulo: 26804 - FISICA APPLICATA
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APPLIED PHYSICS
• International System of Units, type of physical quantities, multiples and submultiples, proportions.
• The Force. Properties and some specific forces. Dynamic laws.
• The pressure, the density, atmospheric pressure and blood pressure.
• The heat. The temperature, specific heat, heat propagation.
• The radioactivity. Nucleus structure, the decay law, notions of nuclear medicine.
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Modulo: 26805 - INFORMATICA
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COMPUTER SCIENCE and SEMINAR
Structure, basic functions and components of a PC. Encoding and digital representation of information.
Operating System functionalities and familis. Human/Computer communication interface. Data storage. File management.
The Microsoft Windows operating system. Graphical user interface,icons. File Explorer, "Start" button. System settings, Organization of folders and data.
Office Automation applications: Word, Excel, PowerPoint
Computer networks
Connection to the network (modem, ADSL, LAN, wireless)
Internet services: WWW; e-mail; search engines
Computer security
Online collaboration
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Modulo: 53261 - SEMINARIO DI INFORMATICA
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COMPUTER SCIENCE and SEMINAR
Structure, basic functions and components of a PC. Encoding and digital representation of information.
Operating System functionalities and familis. Human/Computer communication interface. Data storage. File management.
The Microsoft Windows operating system. Graphical user interface,icons. File Explorer, "Start" button. System settings, Organization of folders and data.
Office Automation applications: Word, Excel, PowerPoint
Computer networks
Connection to the network (modem, ADSL, LAN, wireless)
Internet services: WWW; e-mail; search engines
Computer security
Online collaboration Didactic methods
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Modulo: 000061/1 - BIOCHIMICA
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Lectures + Google Classroom use for communications, exercises and store of useful material.
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Modulo: 009824/2 - CHIMICA MEDICA
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lectures and self-assessment focus
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Modulo: 010216/1 - STATISTICA MEDICA
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The teaching activity of the course is organized in classroom lessons.
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Modulo: 015421/1 - GENETICA MEDICA
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The teaching activity of the integrated course is organized in classroom lessons.
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Modulo: 015440/3 - BIOLOGIA APPLICATA
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The teaching activity of the integrated course is organized in classroom lessons. The teaching material of the course, such as lecture slides, will be uploaded online on the classroom platform.
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Modulo: 26804 - FISICA APPLICATA
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The teaching activity of the integrated course is organized in classroom lessons.
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Modulo: 26805 - INFORMATICA
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The teaching activity of the integrated course is organized in classroom lessons.
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Modulo: 53261 - SEMINARIO DI INFORMATICA
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Frontal lectures and classroom computers Learning assessment procedures
- MEDICAL CHEMISTRY
Multiple-choice written test (4 possible answers) composed by 11 questions about the subjects of the course. Starting points: 10. Each correct answer scores 2 points; no penalties for wrong or not answered question. To pass the exam, it is necessary to score at least 8 points (4 questions), corresponding to 18/30. The final score corresponds to the final grade of the exam. The time allowed is 15 minutes.
BIOCHEMISTRY
Multiple-choice written test (3-4 possible answers with only one correct) composed by 18 questions about the subjects of the course. Each correct answer scores 2 points; no penalties for wrong or not answered question. To pass the exam, it is necessary to score at least 18 points (9 correct answers), corresponding to 18/30 as final grade of the exam. Maximal grade 31 with all correct answers. The time allowed is 30 minutes.
BIOLOGY
Written exam, with the administration of 20 multiple choice questions (5 options). Each correct answer corresponds to 1.55 points, the wrong answers are worth 0 points. Total available time: 1 hour.
GENETICS
Learning assessment procedures
Written test, with the administration of 10 multiple choice questions (3-4 options). Each correct answer corresponds to 3 points, wrong answers are worth 0 points. Total time available: 30 minutes.
APPLIED PHYSICS
Written exam: 15 multiple answer questions
Evaluation: 2 point for right answer, 0 point for wrong answer or missed answer. Duration: 20 min.
To pass the exam, it is necessary to get 18 points over 30.
MEDICAL STATISTICS
A written examination with closed-ended questions.
COMPUTER SCIENCE and SEMINAR
The exams is composed of
1. Practical assignment: a simple project made using the tools shown at the Seminar classes. The maximum score is 15, the passing threshold is 9.
2. Theory test: 15 multiple choice questions on all the topics presented in the Computer Science and Seminar modules. The score is determined as follows: 1 point per correct answer, 0 points per blank or incorrect answer. The test is passed if the score is greater than or equal to 9.
To take the theory test, the student must have obtained a passing score on the practical assignment, possibly in a previous session. To take both in the same session, the project must be handed in at least a week before the date of the theory test.
The final score is the sum of the scores of the two parts.
THE FINAL GRADE IS A ARITHMETIC AVERAGE OF THE MARKS OBTAINED IN EACH TESTS. Reference texts
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Modulo: 000061/1 - BIOCHIMICA
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-Every Biochemistry text can go however synthetic texts are suggested, such as
M. Stefani, N. Taddei, Chemistry, Biochemistry and Applied Biology, Ed Zanichelli or Stefani e Taddei, Chemistry and Biochemistry, Ed Zanichelli.
Otherwise Catani ecc. Appunti di Biochimica, Piccin ed. or Samaja e Paroni, Chimica e Biochimica, Piccin Ed or Bertoldi ecc., Chimica e Biochimica, EdiSES.
+teaching materials provided by teachers.
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Modulo: 009824/2 - CHIMICA MEDICA
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MEDICAL CHEMISTRY
M. Stefani, N. Taddei, Chemistry, Biochemistry and Applied Biology, Ed Zanichelli and teaching materials provided by teachers.
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Modulo: 010216/1 - STATISTICA MEDICA
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• Martin Bland, Statistica Medica, Apogeo Ed. 2009.
• Marcello Pagano, Kimberlee Gauvreau, Fondamenti di Biostatistica, Idelson Gnocchi 2003.
• Bernard Rosner, Fundamentals of Biostatistics, Cengage Learning 2011.
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Modulo: 015421/1 - GENETICA MEDICA
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GENETICS
Neil A., Campbell, Jane B. Reece, Biologia- La genetica, Zanichelli Ed.
M.R. Cummings, Eredità, EdiSES
B. A. Pearce, Genetica, Zanichelli Ed.
Alternatively, after consultation with the teacher, any updated text of Genetics
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Modulo: 015440/3 - BIOLOGIA APPLICATA
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CHIMICA MEDICA E BIOCHIMICA E BIOLOGIA. M.Stefani, N.Taddei, Chimica,Biochimica e Biologia Applicata, Ed. Zanichelli.
Teaching material provided by the teachers, for example lecture slides, uploaded to the online classroom platform.
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Modulo: 26804 - FISICA APPLICATA
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APPLIED PHYSICS:
Material provided by the teacher.
A.H. Cromer, Fisica per medicina - farmacia e biologia, Piccin Editore Padova. II edizione italiana a cura di L. Peruzzo e G. Tornielli.
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Modulo: 26805 - INFORMATICA
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COMPUTER SCIENCE
Lecture notes provided by the teacher or any book for ECDL Full Standard exam preparation, published from 2014 onwards.
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Modulo: 53261 - SEMINARIO DI INFORMATICA
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COMPUTER SCIENCE
Lecture notes provided by the teacher or any book for ECDL Full Standard exam preparation, published from 2014 onwards.
