HUMAN PATOLOGY
Academic year and teacher
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- Versione italiana
- Academic year
- 2022/2023
- Teacher
- SIMONETTA FALZONI
- Credits
- 6
- Didactic period
- Secondo Semestre
Training objectives
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Modulo: 006050 - FISIOPATOLOGIA GENERALE
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GENERAL PHYSIOPATHOLOGY
Learning of basic Pathology: etiology (genetic diseases, environmental pathology). Inflammatory reactions. Alterations of cell proliferation and differentiation. Tumours.
To learn the basic knowledge of pathophysiology of circulation and o other anatomic systems for the correct diagnosis of human disease processes.
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Modulo: 006050/2 - FISIOPATOLOGIA ENDOCRINA
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ENDOCRINE PHYSIOPATHOLOGY
The course has the main objective of treating the pathophysiological basis of the endocrine system and metabolism
The main acquired knowledge will be:
The mechanisms that determine the functional and structural abnormalities of the endocrine glands
The changes that follow the states of excess or defect hormone
The basic acquired abilities will be:
Know and understand the main mechanisms that alter the functions and structure of the endocrine glands
Understand the rationale that underlies of laboratory tests performed for diagnostic purposes and their clinical relapses
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Modulo: 015187/1 - PATOLOGIA GENERALE
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GENERAL PATHOLOGY
Learning of basic Pathology: etiology (genetic diseases, environmental pathology). Inflammatory reactions. Alterations of cell proliferation and differentiation. Tumours.
To learn the basic knowledge of pathophysiology of circulation and o other anatomic systems for the correct diagnosis of human disease processes. Prerequisites
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Modulo: 006050 - FISIOPATOLOGIA GENERALE
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GENERAL PHYSIOPATHOLOGY
Basic knowledge of histology, anatomy, biochemistry, genetics and physiology.
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Modulo: 006050/2 - FISIOPATOLOGIA ENDOCRINA
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ENDOCRINE PHYSIOPATHOLOGY
The student should have adequate prior knowledge on histology and anatomy related to the endocrine system the fundamental concepts of physiology and biochemistry, in particular those related to the endocrine system
Also have passed the exam of Functional and structural sciences human body.
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Modulo: 015187/1 - PATOLOGIA GENERALE
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GENERAL PATHOLOGY
Basic knowledge of histology, anatomy, biochemistry, genetics and physiology. Course programme
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Modulo: 006050 - FISIOPATOLOGIA GENERALE
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GENERAL PHYSIOPATHOLOGY
Atherosclerosis. Haemorrhages. Haemostasis: components and phases. Thrombosis. Embolism. Tissue ischemia. Infarction. Hyperaemia and congestion. Edema. Hypertension and hypotension. Shock: causes and pathogenetic mechanisms. Blood pathophysiology: anaemia and haemorragic disorders. Pathophysiology of digestive system, liver and pancreas. Renal pathophysiology. Modifications of acidic-base balance
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Modulo: 006050/2 - FISIOPATOLOGIA ENDOCRINA
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Endocrine responses and organization of the endocrine system
Mechanisms of the body's response to external stimuli through endocrine responses. Nervous system - endocrine system integration. Organization of the endocrine system: the axes and their functioning.
Pathophysiology and clinic of diseases affecting the endocrine system and metabolism, in particular:
- Thyroid: hypothyroidism, hyperthyroidism, thyroiditis, goiter, thyroid nodule and thyroid neoplasms.
- Phospho-calcium and bone metabolism. Diseases of the parathyroid glands: hyperparathyroidism, hypoparathyroidism.
- Hypothalamic-pituitary system: diseases of the anterior pituitary (pituitary tumors, syndromes of excess and deficiency of pituitary hormones) and posterior pituitary (diabetes insipidus).
- Male and female hypogonadism. Amenorrhea.
- Adrenal: diseases of the cortex (hypoadrenocorticism, Cushing's syndrome, congenital adrenal hyperplasia, hyperaldosteronism) and medulla (pheochromocytoma)
- Endocrine control of hydroelectrolytic balance and blood pressure.
- Multiple endocrine neoplasms of types 1 and 2.
- Diabetes mellitus: classification, diagnosis, pathogenesis of type 1 and 2 diabetes and complications.
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Modulo: 015187/1 - PATOLOGIA GENERALE
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GENERAL PATHOLOGY
Introduction to general pathology. Cell homeostasis. Cell death: necrosis and apoptosis. Acute inflammatory reaction. Soluble mediators and inflammatory cells. Classification of acute inflammatory reactions. Healing and regeneration. Chronic inflammatory response. Interstitial and granulomatosis inflammations. General effects of inflammation: acute phase proteins and fever. Main infectious pulmonary and gastro-intestinal diseases. Modifications of tissue homeostasis: hypertrophy, hyperplasia, atrophy, metaplasia, displasia. Tumours: characteristics of benign and malignant tumours. Molecular basis of cancer. Tumour growth and progression. Local invasion and metastasis. Immune response. Local and general tumour effects. Tumour epidemiology. Carcinogenesis. Tumour diagnosis. Preneoplastic lesions. Didactic methods
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Modulo: 006050 - FISIOPATOLOGIA GENERALE
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GENERAL PHYSIOPATHOLOGY
Lectures
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Modulo: 006050/2 - FISIOPATOLOGIA ENDOCRINA
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Frontal lectures and presentation of problems with interactive methods
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Modulo: 015187/1 - PATOLOGIA GENERALE
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GENERAL PATHOLOGY
Lectures Learning assessment procedures
- GENERAL PATHOLOGY and PHYSIOPATHOLOGY:
Multiple choice test. 15 questions in 15 minutes. 1 point for every correct answer, 0 point for every incorrect or invalid answer. 9 points are necessary to pass the exam.
ENDOCRINE PHYSIOPATHOLOGY:
Oral test lasting 20-30 minutes with 2-3 questions, that will evaluate the acquired knowledge. In addition, the test will evaluate the capacity of connecting the acquired notions. To pass this test it is required to get at least 18 points out of 30.
Final graduation is calculated as arithmetic mean of the three partial marks Reference texts
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Modulo: 006050 - FISIOPATOLOGIA GENERALE
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GENERAL PHYSIOPATHOLOGY
Pontieri, Patologia generale per corsi di laurea in professioni sanitarie, Piccin Editore
Robbins, Le basi patologiche delle malattie vol. 1 Piccin Editore
Stevens, Lowe Patologia generale, Casa Editrice Ambrosiana
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Modulo: 006050/2 - FISIOPATOLOGIA ENDOCRINA
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Teacher’s handouts
Specific topics can be further developed in the following texts:
Lenzi A., Dondero F., D'Armiento M., Guida allo studio dell'Endocrinologia, Società Editrice Universo
Fabrizio Monaco Endocrinologia (per i corsi di laurea delle professioni sanitarie) II edizione (2013) Società Editrice Universo
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Modulo: 015187/1 - PATOLOGIA GENERALE
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GENERAL PATHOLOGY
Pontieri, Patologia generale per corsi di laurea in professioni sanitarie, Piccin Editore
Robbins, Le basi patologiche delle malattie vol. 1 Piccin Editore
Stevens, Lowe Patologia generale, Casa Editrice Ambrosiana
