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ANATOMIC PATHOLOGY I

Academic year and teacher
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Versione italiana
Academic year
2022/2023
Teacher
GIOVANNI LANZA
Credits
5
Didactic period
Secondo Semestre
SSD
MED/08

Training objectives

The Pathology I course provides the systematic treatment of the pathological basis of diseases of the kidney and lower urinary tract, of the male genital system, of the respiratory system, of the mediastinum, of pancreas, liver and biliary tract and of the haemolymphopoietic system.

Knowledge and understanding:
At the end of the course the student will:
- know the basic concepts about the epidemiological, etiopathogenetic, morphological, clinicopathological and biomolecular characteristics of pathological processes of the kidney and lower urinary tract, of the male genital system, of the respiratory system, of the mediastinum, of pancreas, liver and biliary tract and of the haemolymphopoietic system.
- will be able to understand the clinical pictures related to different pathologies of the aforemetioned systems and to understand pathology reports.
- know the biomolecular tests to be performed for target therapies and for immunotherapy in the main types of tumors.
- be aware of gender differences in incidence, diagnosis and treatment of various pathologies of the aforementioned systems.

Applying knowledge and understanding:
At the end of the course the student will have ability:
- to use the pathological information provided by morphology, immunohistochemistry and molecular biology, understanding their value in diagnosis, prognosis and therapy.

Prerequisites

Adequate knowledge of anatomy and histology of the kidney and lower urinary tract, of the male genital system, of the respiratory system, of the mediastinum, of pancreas, liver and biliary tract and of the haemolymphopoietic system.
Knowledge of general pathology, genetics and molecular biology.

Course programme

Urinary system: Kidney: benign and malignant tumors.
Urinary tract: Precancerous lesions and neoplasms.
Male genital tract: Prostate: Prostatic hyperplasia, prostatic carcinoma.
Testis: Germ cell tumors, tumors of sex cord and of gonadal stroma.
Respiratory system: Lung: Pneumonia. Sarcoidosis. Tubercolosis. Lung tumors and metastatic
tumors.
Pleura: Pleuritis. Pleural tumors.
Digestive system
Liver: Acute and chronic hepatitis. Alcoholic liver disease. Intra-hepatic biliary tract pathology. Cirrhosis. Benign and malignant tumors.
Gallbladder and extra-hepatic biliary tract: Lithiasis. Cholecystitis. Cholangitis. Benign and malignant tumors and precancerous lesions.
Pancreas: Pancreatic carcinoma. Neuroendocrine tumors.
Disease of the haemolymphopoietic system: Lymphadenitis. Lymphoid neoplasms: precursor B and T–cell neoplasms, peripheral B and T/NK cell neoplasms. Hodgkin lymphoma. Plasma cell dyscrasias (hints)
Mediastinum: Lymphoma and thymoma

Didactic methods

The Pathology I course provides frontal lectures and on-line assisted teaching. The on-line teaching on moodle platform certification service consists in deepening of some topics presented during the frontal lessons providing, in addition to the teaching material presented during lessons, clinical cases, guidelines and recommendations by scientific societies, scientific articles and learning assessment multiple choice test.

Learning assessment procedures

The learning verification will be carried out by a written exam consisting in 32 questions for a total duration of 30 minutes. The questions will be formulated with multiple choice questions (5 options for each question) relating to all the educational objectives of the course.
Each correct answer will be evaluated 1 point and there will be no penalty for incorrect or non-given answers. The exam mark is assigned in a scale out of thirty: 18/30 is the minimum for passing the exam, achieved by correctly answering to 18 questions, while the maximum mark, 30 cum laude, will be attributed to those who pass the score of 30.

Reference texts

Rubin, Anatomia patologica e Patologia Generale, Piccin Editore
Robbins e Cotran, Le basi patologiche delle malattie, Elsevier Editore