MOLECULAR BASIS OF ENDOCRINE DISEASES
Academic year and teacher
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- Versione italiana
- Academic year
- 2016/2017
- Teacher
- MARIA CHIARA ZATELLI
- Credits
- 1
- Didactic period
- Secondo Semestre
- SSD
- MED/13
Training objectives
- This course aims to provide knowledge on the molecular mechanisms of selected endocrine diseases
The main acquired knowledge will be:
•Mechanism of action of hormones
•Molecular mechanisms of multiple endocrine neoplasias and endocrine diseases due to molecular damages
The basic acquired abilities will be:
•To know which molecular investigations can be performed in the settings of specific endocrine diseases
•To interpret correctly a report dealing with molecular diagnostics of specific endocrine diseases Prerequisites
- The following concepts are mandatory:
•background knowledge in anatomy, biology, physiology and physiopathology of the endocrine system
•background knowledge in biochemistry and molecular biology of hormone mechanism of action Course programme
- The course forecasts 8 hours of teaching. During this time, examples of molecular diagnostics of endocrine diseases mechanisms carried on at the Endocrine Lab will be offered to the students.
Molecular diagnostics of thyroid nodules. Molecular basis of endocrine neoplasms. Familial forms of pituitary adenomas. Pituitary side effects of oncological therapy. RET mutation analysis in Endocrinology. MEN4 Didactic methods
- The course is organized as follows:
•frontal lectures on all the course’s topics;
•visits to the Endocrine Physiopathology at the Section of Endocrinology and Internal Medicine, Dept. of Medical Sciences of the University of Ferrara at the Hospital of Ferrara. After the guided tutorials the students will have free access to the lab for additional individual tests. Learning assessment procedures
- The aim of the exam is to verify at which level the learning objectives previously described have been acquired, by a test lasting 1 hour with 31 questions displaying 4 possible answers (only one is correct); each correct answer is equivalent to 1 point, while each wrong or blank answer is 0 points. The test will evaluate the acquired knowledge and the capacity of connecting the acquired notions. To pass this test it is required to get at least 18 points out of 30
Reference texts
- Teacher’s handouts
Specific topics can be further developed in an Endocrinology text