GENERAL PATHOLOGY
Academic year and teacher
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- Versione italiana
- Academic year
- 2022/2023
- Teacher
- PAOLO PINTON
- Credits
- 7
- Didactic period
- Secondo Semestre
- SSD
- MED/04
Training objectives
- Objective of the general pathology course is the ethiology and the pathogenesis of the diseases. In particular the course will focus on the mechanisms involved in the functional and morphological changes of the acute and chronic inflammatory response, wound healing. The course will also focus on the molecular mechanisms leading to alteration of the growth and cellular differentiation, innate and acquired immunity, immunopathological reaction.
Prerequisites
- Basic knowledge of biochemistry, microbiology and physiology
Course programme
- Concepts of aetiology and pathogenesis
Cellular pathology: necrosis, apoptosis and autophagy
Pathogenesis by physical agents: radiation
Mechanism of action and biotechnological use of bacterial toxins.
Inflammation: acute and chronic, inflammatory cells, endogenous and exogenous mediators of inflammation, exudate, granuloma, systemic reaction to inflammation, wound healing.
Immunology: innate and acquired immunity, lymphoid organs and cells of the immune system, co-operation among cells during the immune response, antigen presentation, T and B lymphocytes, structure and classes of immunoglobulins, hypersensitivity type 1, 2, 3 and 4.
Tumors: Alteration of cell growth and differentiation, epidemiology of tumors, histopathological features of tumor cells, tumor growth and angiogenesis, promotion and initiation, cancerogenesis by chemical, physical and biological agents, oncogenes, metastasis, immunity against tumors. Didactic methods
- Lectures
Learning assessment procedures
- The aim of the examination is to test the level of achievement of learning objectives previously indicated..
A quiz (multiple choice questions) on the basic concepts of the course (Each correct answer = 1 point; each wrong answer = -0.5; no answer = 0)
The time for this test is 1 hour.
It is not allowed to consult texts or use PCs, smart phones, calculators, .... ; Reference texts
- Rubin, Patologia Generale
Robbins, Le basi molecolari delle malattie
Janewa, Immunobiologia.
