GENERAL PATHOLOGY AND PHARMACOLOGY
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- Versione italiana
- Academic year
- 2022/2023
- Teacher
- ANNA LISA GIULIANI
- Credits
- 4
- Didactic period
- Primo Semestre
Training objectives
- Learning of basic Pathology: etiology, inflammatory reactions, alterations of cell proliferation and differentiation, tumours.
Learning of genetic disorders, intracellular accumulations and degenerative connective tissue processes. Learning of main immune-pathologic diseases: hypersensitivity reactions and autoimmune diseases.
The main goal of the course consists in providing knowledge of General Pharmacology related to Pharmacokinetics and Pharmacodynamics and to assess the basic elements for understanding the mechanisms of drug action. The pharmacological effects of some of the most important drugs in the pain therapy e.g. NSAIDs and opioids will be evaluated with the indication in specific clinical cases.
The main knowledge acquired will be:
- general concepts of pharmacokinetics
- general concepts of pharmacodynamics
- evaluation of the drug effects in the pain therapy.
The main skills that are the ability to apply knowledge acquired will be:
- assessment of pharmacokinetic factors determining drug effects, drug mechanisms and toxicity to better clarify the pharmacological effect of the drugs
- evaluation of the basis of the drug effects in the pain therapy for NSAIDs and opioids with the indication in selected clinical cases.
Helping students to understand the most important aspects of Internal Medicine, with a particular focus on cardiovascular diseases and sex/gender-related differences. Prerequisites
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Modulo: 015187/1 - PATOLOGIA GENERALE (mutua dall'attività formativa PATOLOGIA GENERALE - 015187/1 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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GENERAL PATHOLOGY
Basic knowledge of chemistry, biochemistry, physiology, anatomy, biology and general pathology are requested.
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Modulo: 015310/1 - FARMACOLOGIA (mutua dall'attività formativa FARMACOLOGIA - 015310/1 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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PHARMACOLOGY
Basic knowledge of chemistry, biochemistry, physiology, anatomy, biology and general pathology are requested.
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Modulo: 23329 - MEDICINA INTERNA (mutua dall'attività formativa MEDICINA INTERNA - 23329 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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INTERNAL MEDICINE
Basic knowledge of chemistry, biochemistry, physiology, anatomy, biology and general pathology are requested. Course programme
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Modulo: 015187/1 - PATOLOGIA GENERALE (mutua dall'attività formativa PATOLOGIA GENERALE - 015187/1 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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GENERAL PATHOLOGY
Introduction to General Pathology. Cell homeostasis. Cell death: necrosis and apoptosis. Acute inflammation. Formation of exudate. Mediators of inflammation. Characteristics of exudates. Types of inflammatory reactions. Regeneration and repair. Chronic inflammation: general information. Interstitial and granulomatous inflammation. Systemic effects of inflammation. Febrile hyperthermia. Alterations of tissue homeostasis: hypertrophy, hyperplasia, hypotrophy, metaplasia, and dysplasia. Neoplasm: general information. Neoplasms benign and malignant. The molecular basis of cancer. Growth and tumor progression. Local invasiveness and metastasis. Effects of the tumor on the host. Cancer epidemiology. Carcinogens. Diagnosis of tumors. Immunopathology: hypersensitivity reactions. General characteristics of autoimmune diseases. Examples of autoimmune diseases: Hashimoto's thyroiditis, Graves' disease, Type I diabetes mellitus, myasthenia gravis, multiple sclerosis, Sjogren's syndrome, rheumatoid arthritis, inflammatory myopathies, scleroderma, systemic lupus erythematosus.
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Modulo: 015310/1 - FARMACOLOGIA (mutua dall'attività formativa FARMACOLOGIA - 015310/1 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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PHARMACOLOGY
The course forecast frontal lectures where the following topics will be illustrated:
- General principles of Pharmacokinetics and Pharmacodynamics;
- Drug-receptor interaction;
- Agonists, antagonists and allosteric modulators;
- Therapeutic index and drug toxicity;
- Main drugs primarily used in the pain therapy e.g. NSAIDs and opioids.
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Modulo: 23329 - MEDICINA INTERNA (mutua dall'attività formativa MEDICINA INTERNA - 23329 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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INTERNAL MEDICINE
Pathogenesis, diagnosis, and pills of therapy of arterial hypertension, angina, acute myocardial infarction, Takotsubo syndrome, heart failure. Sex/gender related differences of risk factors and cardiovascular diseases. Didactic methods
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Modulo: 015187/1 - PATOLOGIA GENERALE (mutua dall'attività formativa PATOLOGIA GENERALE - 015187/1 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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GENERAL PATHOLOGY
Frontal lectures on the course’s topics through power point presentation (frontal class or videorecorded classroom).
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Modulo: 015310/1 - FARMACOLOGIA (mutua dall'attività formativa FARMACOLOGIA - 015310/1 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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PHARMACOLOGY
Frontal lectures through power point presentation.
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Modulo: 23329 - MEDICINA INTERNA (mutua dall'attività formativa MEDICINA INTERNA - 23329 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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INTERNAL MEDICINE
Frontal lectures on the course’s topics through power point presentation (frontal class). Learning assessment procedures
- The final grade of the integrated course is given by the weighted average of the scores of the partial tests, each compared to the corresponding training credits.
Reference texts
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Modulo: 015187/1 - PATOLOGIA GENERALE (mutua dall'attività formativa PATOLOGIA GENERALE - 015187/1 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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GENERAL PATHOLOGY
For voluntary more-in-depth study:
Pontieri, Patologia e Fisiopatologia generale per Corsi di Laurea in Professioni Sanitarie, Piccin Editore
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Modulo: 015310/1 - FARMACOLOGIA (mutua dall'attività formativa FARMACOLOGIA - 015310/1 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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PHARMACOLOGY
- Rossi F., Cuomo V., Riccardi G., Farmacologia. Principi di base e applicazioni terapeutiche, Ed. Minerva Medica.
- Panus PC, Katzung B, Jobst EE., et al., Farmacologia in riabilitazione, Edi-Ermes.
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Modulo: 23329 - MEDICINA INTERNA (mutua dall'attività formativa MEDICINA INTERNA - 23329 del CdS ORTOTTICA ED ASSISTENZA OFTALMOLOGICA (abilitante alla professione sanitaria di Ortottista ed assistente di oftalmologia) - 1059)
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INTERNAL MEDICINE
All the didactic material is provided to the students, and it is sufficient to pass the exam. For voluntary more-in-depth study:
Rugarli C, Trattato Italiano di Medicina Interna, Ed. Masson
Harrison: Principles of Internal Medicine, McGraw-Hill ed.
Amoroso A, Rossi Fanelli F, Afeltra A, Basili S, Manfredini R, Sasso FC: Semeiotica Medica e Metodologia Clinica, Antonio Delfino Ed.
