PHARMACOLOGY APPLIED TO MOTOR AND SPORTS ACTIVITIES
Academic year and teacher
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- Versione italiana
- Academic year
- 2019/2020
- Teacher
- STEFANIA MERIGHI
- Credits
- 6
- Didactic period
- Secondo Semestre
- SSD
- BIO/14
Training objectives
- The main goal of the course consists in providing to the students the basis for understanding the practice of doping which seems to have an increasing popularity among athletes, not only professionals but also amateurs. Unfortunately, the perception of the problem by those involved and those who work in sports seems to be very inaccurate.
This course is designed to enhance the student's knowledge in the field of pharmacology
The main acquired knowledge will be:
-the ability to address the issues of doping not only as unfair and illegal practice but also as a risk to the health of athletes,
- Know the classification of the main classes of drugs and methods prohibited in sport
The basic acquired abilities (that are the capacity of applying the acquired knowledge) will be:
- to analyze the programme of research and development of new drugs
- to evaluate the possibility of drug therapy to be applied in sports
-to examine critically the new types of alternative medicines on the market Prerequisites
- Good knowledge of chemistry, biochemistry, physiology, anatomy, pathology.
Course programme
- The course forecasts 48 hours of teaching through frontal lectures divided as follows:
Drug development and research (6 hours)
General principles of pharmacology: historical aspects and study on the drugs research and development.
Toxicity (6 hours)
toxicity in preclinical phase- toxicity in clinical trials- Research toxicity: Prous Science Integrity
Clinical studies designed in the process of discovering and proving the effectiveness of medical drugs. Topics covered include pharmacokinetic, pharmacodynamic profile and therapeutic effects of:
the main classes of biotechnological drugs (4 hours)
Food supplements (2 hours)
Generics (4 hours)
Homeopathic remedies (2 hours)
Drugs in the world (2 hours)
Doping (18 hours)
prohibited list (WADA); Stimulants, narcotics, anabolic agents, Diuretics, Corticosteroids, Alcohol. Antiasthmatic agents; anti-inflammatory drugs.
The main laboratory tests for the assessment of toxicity (4 hours)
Cell culture for drug screening. Notes on the use of molecular biology techniques in toxicology (northern and western blot, in situ hybridization, antisense oligonucleotides, PCR, cloning, transgenic animals). Didactic methods
- The course is organized through frontal lectures on all the course’s topics.
Learning assessment procedures
- The aim of the exam is to verify at which level the learning objectives previously described have been acquired.
One test (16 multiple choice questions) based on all the topics covered in the course with the aim of evaluating how deeply the student has studied the subject and how he is able to understand the basic topics analyzed.
Each question is worth 2 points if correct; wrong answer or no answer 0 points; limited to 16 correct answers match score of 30/30 cum laude; 9 correct answers match score of 18/30 .
Time for the text is 1 hour. Reference texts
- Teacher’s handouts
Specific topics can be further developed in the following texts.
FARMACOLOGIA: Principi di base e applicazioni terapeutiche. Ed. F. Rossi, V. Cuomo, C. Riccardi- Edizioni Minerva Medica, Torino 2005
Mottram: Farmaci e Sport - Casa Editrice Ambrosiana
