MOLECULAR BASES OF PHYSICAL EXERCISE
Academic year and teacher
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- Versione italiana
- Academic year
- 2019/2020
- Teacher
- GIANLUCA AGUIARI
- Credits
- 3
- Didactic period
- Secondo Semestre
- SSD
- BIO/10
Training objectives
- The aim of the course is to teach some concepts of molecular and cellular biochemistry linked to physical exercise. The signal transduction and muscle contraction, doping and health risks. Study of neuromuscular diseases. The student will learn new knowledge that will be useful in athletic training.
Prerequisites
- Chemistry and biochemistry skills
Course programme
- Gene structure: promoters, introns and exons.
Genetic information: transcription, processing and translation.
Muscle development and signal transduction. The role of mTOR. Erythropoiesis regulation and erythropoietin function.
Genetic and pharmacological doping.
Actin/Myosin regulation. Calcium release and muscle contraction.
Muscle differentiation. Muscle specific transcription factors.
Muscle growth and regeneration.
Genes associated with muscle diseases: Duchenne disease. Dystrophin function.
Biochemistry of exercise and cellular adaptation.
Biochemical training. Didactic methods
- Frontal lessons
Learning assessment procedures
- Written test with 31 questions; every question is composed by three answers one true and two false. Exam time: one hour. The test is passed with a minimum of 18 right answers. By answering exactly all the questions, you get the praise.
Reference texts
- Material gave from professor.
Nicoletta Zoppi e Marina Colombi, Biologia e genetica del muscolo, Edises
A. Di Giulio, A. Fiorilli, C. Stefanelli, Biochimica per le scienze motorie, Casa Editrice Ambrosiana
