FORENSIC MEDICINE, GENERAL PHARMACOLOGY AND DOPING
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- Versione italiana
- Academic year
- 2022/2023
- Teacher
- STEFANIA MERIGHI
- Credits
- 9
- Didactic period
- Primo Semestre
Training objectives
- The main goal of the course consists in providing basic knowledges of General Pharmacology related to Pharmacokinetics and Pharmacodynamics. Moreover, the course aims to provide the basic elements for understanding the mechanisms of drug action, the therapeutic index and the drug toxicity. The pharmacological effects of some of the most important drugs used in the life and in the pain therapy will be assessed.
The main knowledge acquired will be:
- general concepts of pharmacokinetics
- general concepts of pharmacodynamics
- mechanisms of drug action, correlation with different classes of the receptors and evaluation of the drug effects in some cardiovascular and neurodegenerative pathologies
-the classification of the main classes of drugs and methods prohibited in sport
The basic acquired abilities (that are the capacity of applying the acquired knowledge) will be:
-assessment of pharmacokinetic factors determining drug effects, drug mechanisms and toxicity to better clarify the pharmacological effect of the drugs
-knowledge of the cellular and molecular mechanisms at the basis of the drug effects.
-to analyze the programme of research and development of new drugs
-to evaluate the possibility of drug therapy to be applied in sports
-to examine critically the new types of alternative medicines on the market
- Principles of forensic medicine and forensic toxicology Prerequisites
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Modulo: 008007 - MEDICINA LEGALE
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Knowledge of the basic principles of biology, pharmacology and toxicology.
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Modulo: 65968 - FARMACOLOGIA GENERALE, SPECIALE E DOPING
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Basic knowledge of chemistry, biochemistry, physiology, anatomy and biology are requested.
Knowledge of the basic principles of biology, pharmacology and toxicology Course programme
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Modulo: 008007 - MEDICINA LEGALE
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Ethical code
Ethics
Bioethics
Ethics and standards
Private insurance
Biological damage
Forensic Toxicology (substances and methodologies used for sports doping)
Anti-doping sports rules
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Modulo: 65968 - FARMACOLOGIA GENERALE, SPECIALE E DOPING
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The course forecasts 48 hours of teaching through frontal lectures divided as follows:
- General principles of Pharmacokinetics and Pharmacodynamics
- Drug research and development
- Pharmacokinetics: administration routes; absorption; distribution; metabolism; excretion; bioavailability
- Drug-receptor interaction and dose-response curves
- Agonists, antagonists and allosteric modulators
- Therapeutic index and drug toxicity
- Classification of the receptors and mechanism of the drug-receptor interaction
- Gender pharmacology: main differences in pharmacokinetics and pharmacodynamics
- Main drugs primarily used e.g. benzodiazepines, NSAIDs and opioids
- The drugs in the most common cardiovascular and neurodegenerative diseases
-Generic drugs and homeopathic remedies
-The main classes of biotechnological drugs
-Doping, prohibited list (WADA): Stimulants, narcotics, anabolic agents, Diuretics, Corticosteroids, Antiasthmatic agents Didactic methods
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Modulo: 008007 - MEDICINA LEGALE
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Frontal lectures on the course’s topics through power point presentation.
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Modulo: 65968 - FARMACOLOGIA GENERALE, SPECIALE E DOPING
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Frontal lectures on the course’s topics through power point presentation. Learning assessment procedures
- The aim of the exam is to verify at which level the learning objectives previously described have been acquired. The aim of this examination is to evaluate how deeply the student has studied the subject and how he is able to understand the basic topics analyzed. The exam is based on 31 multiple choice questions with four answers each; the question is worth one point if correct, wrong answer or no answer 0 points. To pass this test it is required to get at least 18 points. The time allowed for this test is 1 hour.
Reference texts
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Modulo: 008007 - MEDICINA LEGALE
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Mottram D.R., Farmaci e sport, Casa Ed. Ambrosiana
Rossi F., Cuomo V., Riccardi G., Farmacologia. Principi di base e applicazioni terapeutiche, Ed. Minerva Medica
Power point presentation of the lessons
CODICE SPORTIVO ANTIDOPING
Documento tecnico-attuativo del Codice Mondiale Antidoping WADA
e dei relativi Standard internazionali
Medicina Legale e Bioetica
(Per I corsi di laurea delle professioni sanitarie)
Tagliaro
Ed Piccin
Compendio di Tossicologia Forense
Aspetti analitici, interpretativi e giuridici
Bertol-Vaiano
Ed. Esculapio
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Modulo: 65968 - FARMACOLOGIA GENERALE, SPECIALE E DOPING
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Mottram D.R., Farmaci e sport, Casa Ed. Ambrosiana
Rossi F., Cuomo V., Riccardi G., Farmacologia. Principi di base e applicazioni terapeutiche, Ed. Minerva Medica
Power point presentation of the lessons
